7.2.2 Special Practices

  • Animal care staff, laboratory and routine support personnel must be provided a medical surveillance program as dictated by the risk assessment, and administered appropriate immunizations for agents handled or potentially present, before entry into animal rooms.  When appropriate, a base line serum sample should be stored.
  • Procedures involving a high potential for generating aerosols should be conducted within a biosafety cabinet or other physical containment device.  When a procedure cannot be performed within a biosafety cabinet, a combination of personal protective equipment and other containment devices must be used.  Consideration should be given to the use of restraint devices and practices that reduce the risk of exposure during animal manipulations (e.g., physical restraint devices, chemical restraint medications, etc).
  • Decontamination is recommended for all potentially infectious materials and animal waste before movement outside the areas where infectious materials and/or animals are housed or are manipulated by an appropriate method (e.g. autoclave, chemical disinfection, or other approved decontamination methods).  This includes potentially infectious animal tissues, carcasses contaminated bedding, unused feed, sharps, and other refuse.  Consideration should be given to means for decontaminating routine husbandry equipment, sensitive electronic and medical equipment.
  • Materials to be decontaminated outside of the immediate areas where infectious materials and/or animals are housed or are manipulated must be placed in a durable, leak proof, covered container and secured for transport.  The outer surface of the container is disinfected prior to moving materials.  The transport container must contain a universal biohazard label.  Develop and implement an appropriate waste disposal program in compliance with applicable institutional, local and state requirements.  Autoclaving of content prior to incineration is recommended.
  • Equipment, cages, and racks should be handled in a manner that minimizes contamination of other areas.  Equipment must be decontaminated before repair, maintenance, or removal from the areas where infectious materials and/or animals are housed or are manipulated.  Spills involving infectious materials must be contained, decontaminated, and cleaned up by staff properly trained and equipped to work with infectious material.
  • Incidents that may result in exposure to infectious materials must be immediately evaluated and treated according to procedures described in the safety manual.  All such incidents must be reported to the animal facility supervisor or personnel designated by the institution.  Medical evaluation, surveillance, and treatment should be provided as appropriate and records maintained.