BSL2 builds upon BSL1 and is suitable for work involving agents that pose moderate hazards to personnel and the environment. It differs from BSL1 in that:
Laboratory personnel have specific training in handling pathogenic agents and are supervised by scientists competent in handling infectious agents and associated procedures.
Access to the laboratory is restricted when work is being conducted.
All procedures in which infectious aerosols or splashes may be created are conducted in biological safety cabinets or other physical containment equipment.