A number of procedures carried out in the laboratory and animal facility offers the potential for either direct or indirect exposure by the oral route. The procedure that offers the greatest potential for exposure by ingestion is mouth pipetting. Clearly, such exposures are completely avoidable through the use of mechanical pipetting devices. Indirect oral exposures can be avoided by practicing good personal hygiene that includes regular hand washing and not placing any objects, including fingers, into the mouth. Wearing a surgical mask or face shield will serve as protection against splashes or splatters of biohazardous material into the mouth.